Synthetic Biology

We have several projects focused on advancing the synthetic biology toolkit for the low cost high throughput construction of microbial strains. Combined with high throughput micro-fermentation capabilities, these new tools have the potential to dramatically speed up the Design, Build, Test & Learn (DBTL) Cycle in synthetic biology.

Some Recent Publications:

Managing the SOS Response for Enhanced CRISPR-Cas-based Recombineering in E. coli Through Transient Inhibition of Host RecA Activity, Eirik Adim Moreb, Benjamin Hoover, Adam Yaseen, Nisakorn Valyasevi, Zoe Roecker, Romel Menacho-Melgar, and Michael D. Lynch. ACS Synthetic Biology. (available online) http://pubs.acs.org/doi/pdf/10.1021/acssynbio.7b00174